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Senior Scientist: Protein engineering

Company: NJ Biopharmaceuticals LLC
Location: Princeton
Posted on: January 16, 2022

Job Description:

NJ Bio is a growing CRO that provides integrated chemistry and biology services to the biotech and pharma sectors. Main services include multistep organic synthesis, medicinal chemistry, bioconjugation, -and flow chemistry. The company is headquartered in North Brunswick, NJ, with an additional chemistry facility in Bristol, PA. NJ Bio is affiliated with Amar Chemistry in India for flow chemistry, and process chemistry .The selected candidate will work on the preparation of bioconjugates (e.g., antibody-drug conjugates, protein-drug conjugates, protein-peptide conjugates, peptide-drug conjugates, protein-oligonucleotide conjugates, protein-fluorophore conjugates, protein-chelator conjugates). -This position will work under the tutelage of a senior chemist or the director of Bioconjugation Chemistry. This role requires excellent communication skills and the ability to work in a dynamic and collaborative environment. -This position also offers significant growth opportunities within our growing organization. -Desired Qualifications - - - - - - - - - -Ph.D. in Bio Chemistry, Biology, Molecular Biology or related discipline, plus 3+ years of related experience in a pharmaceutical industry setting. - - - - - - - - -Preparation and purification of bioconjugates ( - - - - - - - - -Strong background in antibody/protein engineering and molecular biology. - - - - - - - - -Experience in cell-based assays would be an important asset. - - - - - - - - -Experience in monoclonal antibody design & development and biophysical characterization (i.e, FPLC, HPLC, UPLC and mass spectrometry). - - - - - - - - -Working knowledge in mammalian cell culture including 3D cell culture. - - - - - - - - -Excellent written and verbal communication skills that allows to work in a highly interactive team environment. - - - - - - - - -Works creatively, proactively and collaboratively with other departments to support complex scientific projects. - - - - - - - - -Must have the ability to manage several projects simultaneously. - - - - - - - - -Adherence to organizational EHS policies and maintenance of clean, safe workplace per established procedures. - - - - - - - - -Willingness to use technological advancements to improve processes. - - - - - - - - -Can require work at both the North Brunswick, NJ and Bristol PA sites. - -Education and Other Skills: - - - - - - - - - -BS, MS or PhD Bio-Chemistry, Biology, Molecular Biology or related discipline. PhD with 3+ years of experience (MS or BS with 5+ years of experience will be considered). - - - - - - - - -Extensive experience in bioconjugation (mg- to multi-gram) would be preferred - - - - - - - - -In dept exposure to the bioanalytical characterization and development of protein and bioconjugate therapeutics. - - - - - - - - -Management/supervisory experience is essential - - - - - - - - -Demonstrable experience in developing scalable processes for the preparation of conjugates preferred (i.e tech transfer, cGMP). - - - - - - - - -Possess critical thinking and problem-solving skills.NJ Bio offers a competitive compensation and benefits package. -

Keywords: NJ Biopharmaceuticals LLC, Trenton , Senior Scientist: Protein engineering, Engineering , Princeton, New Jersey

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