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Principal Scientist Cellular Immunology

Company: Bristol Myers Squibb
Location: Princeton
Posted on: November 19, 2021

Job Description:

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. Principal Scientist in Discovery Biology - Cellular Immunology Job summary/description Bristol-Myers Squibb is looking for a highly motivated and experienced immunologist to join the Discovery Biology Immunology team located in Lawrenceville, NJ. This individual will lead discovery efforts aimed at modulating immune response and tolerance induction in autoimmune diseases, including biology leadership for early target identification, validation, and lead optimization. The successful candidate will work in close collaboration with multiple cross-functional teams, utilizing human data sets to identify new drug targets and pathways of interests. The candidate may lead a small team, including both direct and indirect supervision of scientists, and is expected to plan, direct, and execute laboratory research identification for early discovery research projects. Roles and Responsibilities * Act as a subject matter expert, with knowledge of principles and concepts in immune tolerance mechanisms, actively participate in internal and external scientific meetings through presentations and critical evaluation of both internal results and emerging scientific literature. * Effectively collaborate in highly matrixed organization to drive new target identification and validation and the advancement of therapeutic candidates. * Biology lead for discovery program for autoimmune diseases indication., driving biology strategy and implementation * Mentor and manage 1-2 direct reports to develop and execute laboratory research or studies protocol-related activities Required Experience and Skills: * Ph.D. in Immunology or equivalent advanced biology degree, with 5+ years of additional relevant experience * Considerable laboratory expertise that spans molecular and cellular research as exemplified by research publications and/or patents. * Thorough knowledge of experimental design, and a high level of technical laboratory skills (including cell culture, immunoassays, protein signaling, qPCR technology platforms, high parameter flow cytometry and imaging) together with an ability to interpret results, present findings in scientific meetings * Deep knowledge of human immunology and autoimmune diseases * Experience with mining large datasets in collaboration with bioinformaticians to understand disease pathophysiology * Demonstrated expertise in executing target identification strategies including the design, implementation, and validation of targets, by use of genome engineering techniques and genetic perturbation (eg shRNA, CRISPR) is required. * Strong leadership, communication and problem-solving skills, and experience in participating in and/or leading multi-disciplinary project teams. Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture. To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S. Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to Visit to access our complete Equal Employment Opportunity statement. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Keywords: Bristol Myers Squibb, Trenton , Principal Scientist Cellular Immunology, Healthcare , Princeton, New Jersey

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