Senior Scientist - Heme/Onc - Translational IPS
Company: Disability Solutions
Location: Princeton
Posted on: October 19, 2024
Job Description:
Working with UsChallenging. Meaningful. Life-changing. Those
aren't words that are usually associated with a job. But working at
Bristol Myers Squibb is anything but usual. Here, uniquely
interesting work happens every day, in every department. From
optimizing a production line to the latest breakthroughs in cell
therapy, this is work that transforms the lives of patients, and
the careers of those who do it. You'll get the chance to grow and
thrive through opportunities uncommon in scale and scope, alongside
high-achieving teams rich in diversity. Take your career farther
than you thought possible.Bristol Myers Squibb recognizes the
importance of balance and flexibility in our work environment. We
offer a wide variety of competitive benefits, services and programs
that provide our employees with the resources to pursue their
goals, both at work and in their personal lives. Read more: .When
you join BMS, you are joining a diverse, high-achieving team united
by a common mission. The Informatics and Predictive Sciences (IPS)
mission is to Pioneer, Partner and Predict to drive transformative
insights for patient benefit. IPS conducts applied computational
research in areas that include genomic, structural and molecular
informatics, computational and systems biology, patient selection
and translational biomarker research, and broader fields including
knowledge science, epidemiology and machine learning-across the
full lifecycle of drug discovery and development and across all
therapeutic areas at BMS. We do this in close partnership with
scientific and clinical experts in the field, both inside and
outside the company." We perform innovative science to empower key
data-driven decisions across a rich pipeline of next-generation
medicines. In doing so, our work transforms the lives of patients,
as well as our own lives and careers.Here, you'll get the chance to
grow and thrive through opportunities that are uncommon in scale
and scope. You'll pursue innovative ideas while advancing
professionally alongside some of the brightest minds in
biopharma.We seek a talented, collaborative inter-disciplinary
computational scientist to work on the analysis, statistical
modeling and generation of hypotheses from high-dimensional
molecular profiling data. This individual will play a key
scientific role leveraging innovative computational analysis
strategies and rich patient data to empower data-driven decisions
alongside BMS colleagues in our Informatics & Predictive Sciences
department and in collaboration with internal partners in drug
discovery and translational medicine research teams. Analysis
scenarios will involve applying cutting-edge bioinformatics,
statistics, and machine learning/AI methods; working with clinical
and large-scale omics data and biomarker data sets that could
include WGS/WES, RNA-Seq, scRNA-Seq, IHC, Spatial Transcriptomics,
etc; from BMS's industrial-leading late-stage oncology clinical
studies; influencing development strategies and advancing BMS
hematology/oncology pipeline. This position offers the exciting
opportunity to make major contributions to scientific knowledge of
cancer disease biology, and to directly impact treatment of cancer
patients. The position would suit an individual with strong
computational capabilities, experience in hematology/oncology
bioinfotrmatics and excellent communication and collaboration
skills. Applications are encouraged from those involved in
innovative translational research for hematology and/or solid tumor
indications in clinical or industrial research environments. The
role offers the opportunity to impact directly the delivery of
truly transformational and life-changing therapies in key diseases
of unmet medical need. Responsibilities
- Apply computational methods to molecular profiling datasets and
develop hypotheses to stratify patients and prioritize indications,
guiding clinical oncology development and reverse translation.
- Perform analysis of clinical and biomarker datasets (e.g.,
large-scale -omics datasets including RNASeq, and Whole
Exome/Genome Sequencing) and derive clinically meaningful
interpretations.
- Identify potential biomarkers for patient enrichment strategies
and gain mechanistic insights of responses and resistances to
treatments of interest.
- Drive in-depth analysis of stratified patient data to elucidate
biological and driver mechanisms in key oncology indications
(integrating multiple omics datasets, including scRNAseq).
- Work with colleagues in the Informatics & Predictive Sciences
group to identify drivers of disease heterogeneity and potential
therapeutic targets for patients in unmet need.
- Collaborate with experimental teams in the iterative validation
of therapeutic and mechanistic therapeutic hypotheses.
- Summarize analysis results and report conclusions to BMS
decision-making bodies. Basic Qualifications:
- Bachelor's Degree 7+ years of academic / industry
experience
- Or Master's Degree 5+ years of academic / industry
experience
- Or PhD 2+ years of academic / industry experiencePreferred
Qualifications:
- Ph.D. or M.S. with 2+ years of experience in computational
biology, bioinformatics, statistics or related fields. Experience
in biotech or pharmaceutical industries is a plus.
- Strong experience in the use of a high-level programming
language such as R, MATLAB, Python or Perl for complex data
analysis and reproducible research practices is a must.
- Substantial experience working with Next Generation Sequencing
datasets, including RNAseq, scRNAseq, Whole-Genome, Whole-Exome
Sequencing and ChipSeq.
- Familiarity with contemporary cloud and high-performance
computing environments.
- Expertise in application of contemporary machine-learning/AI
approaches.
- Ability to work both independently and collaboratively, and to
handle several concurrent, fast-paced projects while conforming
with rigorous requirements of clinical studies.
- Strong problem-solving and collaboration skills, rigorous and
creative thinking.
- Excellent communication, data presentation, and visualization
skills.
- Fluent written and verbal English language communication. The
starting compensation for this job is a range from $109,000 -
150,700, plus incentive cash and stock opportunities (based on
eligibility). The starting pay takes into account characteristics
of the job, such as required skills and where the job is performed.
Final, individual compensation is decided based on demonstrated
experience. For more on benefits, please visit our BMS Careers
site. Eligibility for specific benefits listed in our careers site
may vary based on the job and location.Benefit offerings are
subject to the terms and conditions of the applicable plans then in
effect and may include the following: Medical, pharmacy, dental and
vision care. Wellbeing support such as the BMS Living Life Better
program and employee assistance programs (EAP). Financial
well-being resources and a 401(K). Financial protection benefits
such as short- and long-term disability, life insurance,
supplemental health insurance, business travel protection and
survivor support. Work-life programs include paid national holidays
and optional holidays, Global Shutdown days between Christmas and
New Year's holiday, up to 120 hours of paid vacation, up to two (2)
paid days to volunteer, sick time off, and summer hours
flexibility. Parental, caregiver, bereavement, and military leave.
Family care services such as adoption and surrogacy reimbursement,
fertility/infertility benefits, support for traveling mothers, and
child, elder and pet care resources. Other perks like tuition
reimbursement and a recognition program. If you come across a role
that intrigues you but doesn't perfectly line up with your resume,
we encourage you to apply anyway. You could be one step away from
work that will transform your life and career. Uniquely Interesting
Work, Life-changing CareersWith a single vision as inspiring as
Transforming patients' lives through science--- , every BMS
employee plays an integral role in work that goes far beyond
ordinary. Each of us is empowered to apply our individual talents
and unique perspectives in an inclusive culture, promoting
diversity in clinical trials, while our shared values of passion,
innovation, urgency, accountability, inclusion and integrity bring
out the highest potential of each of our colleagues.On-site
Protocol BMS has a diverse occupancy structure that determines
where an employee is required to conduct their work. This structure
includes site-essential, site-by-design, field-based and
remote-by-design jobs. The occupancy type that you are assigned is
determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned
facility. Site-by-design roles may be eligible for a hybrid work
model with at least 50% onsite at your assigned facility. For these
roles, onsite presence is considered an essential job function and
is critical to collaboration, innovation, productivity, and a
positive Company culture. For field-based and remote-by-design
roles the ability to physically travel to visit customers, patients
or business partners and to attend meetings on behalf of BMS as
directed is an essential job function. BMS is dedicated to ensuring
that people with disabilities can excel through a transparent
recruitment process, reasonable workplace
accommodations/adjustments and ongoing support in their roles.
Applicants can request a reasonable workplace
accommodation/adjustment prior to accepting a job offer. If you
require reasonable accommodations/adjustments in completing this
application, or in any part of the recruitment process, direct your
inquiries to . Visit to access our complete Equal Employment
Opportunity statement. BMS cares about your well-being and the
well-being of our staff, customers, patients, and communities. As a
result, the Company strongly recommends that all employees be fully
vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest
and conviction records, pursuant to applicable laws in your area.If
you live in or expect to work from Los Angeles County if hired for
this position, please visit this page for important additional
information: Any data processed in connection with role
applications will be treated in accordance with applicable data
privacy policies and regulations.
Keywords: Disability Solutions, Trenton , Senior Scientist - Heme/Onc - Translational IPS, Other , Princeton, New Jersey
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