(Sr). Scientist, Downstream Process Development
Company: GenScript
Location: Pennington
Posted on: October 28, 2025
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Job Description:
About GenScript GenScript Biotech Corporation (Stock Code:
1548.HK) is a global biotechnology group. Founded in 2002,
GenScript has an established global presence across North America,
Europe, the Greater China, and Asia Pacific. GenScript's businesses
encompass four major categories based on its leading gene synthesis
technology, including operation as a Life Science CRO, enzyme and
synthetic biology products, biologics development and
manufacturing, and cell therapy. GenScript is committed to striving
towards its vision of being the most reliable biotech company in
the world to make humans and nature healthier through
biotechnology. About ProBio ProBio proactively provides end-to-end
CDMO service from drug discovery to commercialization with
proactive strategies, professional solutions and efficient
processes in cell and gene therapy, vaccine, biologics discovery
and antibody protein drug to accelerate drug development for
customers. ProBio’s total cell and gene therapy solution covers CMC
of plasmid and virus for IND filing as well as clinical
manufacturing and commercial manufacturing. Position Overview? The
position reports to the Associate Director, Downstream Viral Vector
Process Development & MSAT Department. This role is ideally suited
for a dynamic bench-focused individual to support/lead translation
of research process to GMP-compliant manufacturing, and will
develop, scale-up, and evaluate the technology transfer of viral
vector processes. This is a great opportunity to join a fast-paced
company, develop, and expand technical expertise to lead by example
and potentially lead a small team in the near future. Hands-on
experimental work in the development and optimization of downstream
unit operations (TFF, Affinity/Ion Exchange/multimodal
Chromatography, Viral clearance, Sterile filtration, etc.) for
viral vector manufacturing process. Contribute to the planning,
design, and execution of AAV/LVV purification-related experiments
to analyze, interpret, and report data summary packages. Interact
and collaborate with internal/external partnerships to evaluate and
implement new bioprocessing technologies and strategies. Interact
with cross functional teams (Analytic team, MFG, Supply chain,
Facility, QA, QC) to support process technology transfer, cGMP risk
evaluation, and deviation management. Maintain and follow detailed
and comprehensive project timelines. Support in the preparation of
CMC sections for regulatory submissions (IND, Annual Reports, and
BLA), invention disclosures, progress reports, and publications.
Present updates to project or upper management teams on process
development and manufacturing support activities. Read and
understand scientific literature in gene and cell therapy. Use the
knowledge to generate ideas and contribute to process design and
development. Perform other duties as assigned based on business
needs. Qualifications: Bachelor’s degree with 3-7 years, or
Master’s or Ph.D. degree with 1-3 years’ relevant industry
experience in Chemical/Biochemical Engineering, Biological
Sciences, or a related scientific discipline in biotech development
with particular experience in gene and cell therapy product design.
Experience with LVV and AAV process development is a plus. Previous
experience in viral vector process development and manufacturing is
highly preferred. Strong understanding of process scale-up and
scale-down modeling. Good understanding of Design of Experiment
(DOE) and statistical analysis. Experience in CMC regulatory
affairs for FDA, and EMA is a plus. Strong organizational skills
and detailed documentation abilities are required. Work
independently in hands-on laboratory setting, self-motivated to
learn and develop new techniques. Strong interpersonal, verbal, and
written communication skills. Results oriented, be able to
effectively prioritize and complete tasks on time. Collaboration
and teamwork. Must be comfortable in a fast-paced, multi-tasking
biotech environment. Compensation: The salary range, dependent upon
experience level, is $80,000 - $110,000 annually. LW PB GenScript
USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action
employer committed to attracting, retaining, and maximizing the
performance of a diverse and inclusive workforce. It is the
Company's policy to ensure equal employment opportunity without
discrimination or harassment based on race, color, religion, sex
(including pregnancy, childbirth, or related medical conditions),
sexual orientation, gender identity or expression, age, disability,
national origin, marital or domestic/civil partnership status,
genetic information, citizenship status, uniformed service member
or veteran status, or any other characteristic protected by law.
GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.
Please note: Genscript USA Inc./ProBio Inc. will only contact
candidates through verified application sources. GenScript/Probio
does not request personal information from candidates through
individual email or any other platform.
Keywords: GenScript, Trenton , (Sr). Scientist, Downstream Process Development, Science, Research & Development , Pennington, New Jersey
