Senior Engineer, Manufacturing Science and Technology

Company: Century Therapeutics, Inc.
Location: Philadelphia
Posted on: February 16, 2026

Job Description:

Job Description Job Description Description: Position Title: Senior Engineer, Manufacturing Science and Technology Company Background: Century Therapeutics is an innovative biotechnology company building an industry-leading allogeneic iPSC-derived cell therapy platform. This platform integrates cutting-edge gene editing, protein engineering, technical development, and manufacturing capabilities to generate allogeneic, iPSC-derived NK and T cell therapies for cancer, autoimmune, and inflammatory diseases. Century’s foundational technology is built on induced pluripotent stem cells (iPSCs), which have an unlimited self-renewing capacity. This enables complex cellular engineering to produce controlled cell banks of modified cells that can be expanded and differentiated into desired immune effector cells, which can supply vast amounts of allogeneic, homogeneous therapeutic products. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cell products for the treatment of cancer and autoimmune and inflammatory diseases with significant unmet medical needs. Role: The Senior Engineer, Manufacturing Science and Technology will be responsible for developing, scaling up, implementing, and executing manufacturing processes for Century’s cellular therapy programs. The candidate will be expected to lead a team responsible for tech transfers, implement processes into our in house GMP manufacturing facility, and be a hands on operator for the Phase I manufacturing campaign. This role is also responsible for ongoing process development on these programs including scale up and characterization. This role requires extensive collaboration with internal and external teams. The successful candidate will need strong scientific background, interpersonal skills, and ability to work collaboratively with other groups across organizations. This role is based in Branchburg, NJ. Requirements: Responsibilities: • Lead team responsible for tech transfers and implementation of iPSC derived cell process • Develop, execute, analyze, and document process development and scale up experiments • Identify and critically assess opportunities to improve cell therapy platform, such as manufacturing of cell products derived from induced pluripotent stem cells. • Collaborate with internal and external team members • Author and review technical documents (batch records, SOPs, reports, memos, etc.) • Author and review CMC documents for regulatory filings (e.g. IND, BLA) in collaboration with other parts of organization • Foster a collaborative and scientifically rigorous team culture. • Represent Century at external conferences and/or meetings? Qualifications: • PhD in biological, technical, or cell engineering field with 4-6 years relevant experience, or BS/MS degree with 10 years of relevant professional experience. Requirements: • Experience in design, optimization, scale-up, bioreactors, process control, and technology transfer of cell culture unit operations. • Hands-on experience with analytical methods typically used in the manufacture and characterization of cell therapies or biological products • Mammalian cell culture using closed system and automated/dynamic technologies • Proficiency with statistical methods for data analysis (e.g., JMP, GraphPad Prism) Century Therapeutics Inc. is an Equal Employment Opportunity/Affirmative Action Employer - Minority/Female/Disability/Veteran. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or veteran status or any other characteristic protected by federal, state, or local law.

Keywords: Century Therapeutics, Inc., Trenton , Senior Engineer, Manufacturing Science and Technology, Science, Research & Development , Philadelphia, New Jersey